Is morphine-induced sedation synonymous with analgesia during intravenous morphine titration?

Age adapted morphine titration produces equivalent analgesia

Relationships between measurement of pain using visual analog score and morphine requirements during postoperative intravenous morphine titration.

BACKGROUND Although intravenous morphine titration is widely used to obtain rapid and complete postoperative pain relief, the relationship between measurement of pain and morphine requirements varies, and the evolution of pain during titration is poorly understood. METHODS Intravenous morphine titration was administered as a bolus of 2 (body weight < or = 60 kg) or 3 mg (body weight > 60 kg) ...

Postoperative spinal analgesia with morphine.

Patients with pain after operation received morphine hydrochloride intrathecally in doses of 0.02 mg kg-1 (n = 30) and 0.2 mg kg-1 (n = 30). The high-dose group showed slightly longer-lasting and more potent analgesia than the low-dose group. Sedation, decreases in heart rate and systolic arterial pressure, oliguria, nausea and urinary retention were more frequent in the high-dose group. Two pa...

[Comparison of intravenous and epidural morphine analgesia after thoracotomy.].

BACKGROUND AND OBJECTIVES Patients undergoing thoracotomy experience severe postoperative pain. This study aimed at evaluating postoperative analgesia with the association of intravenous and epidural morphine as compared to a single route. METHODS Participated in this study 20 patients of both genders, physical status ASA I, II or III, scheduled for thoracotomy. Patients were premedicated wit...

Morphine for post-caesarean section analgesia: intrathecal, epidural or intravenous?

INTRODUCTION Good analgesia is important after a caesarean section but there are no studies to date that compared intrathecal (IT), epidural (EP) and intravenous patient-controlled analgesia (IV PCA) morphine for post-caesarean section analgesia. In this study, we compared the differences in the quality of analgesia and side effects rendered by IT, EP and IV PCA morphine for post-caesarean sect...